Ryan’s use as a given name was inspired by the surname Ryan, a variation of the Irish O’Riain meaning "son of Rían." Rían is composed of the Irish-Gaelic elements rí, meaning "king" and an, a diminutive suffix. Ryan is considered a unisex name in the US, where variant spellings Ryann and Ryanne are also valid for girls.

This ultrapopular boys' name is rapidly becoming a hot name for girls; admired for its buoyant Irish spirit.