The name Guadalupe is a girl's name of Spanish origin meaning "river of black stones". Guadalupe is ranked #724 on our popularity charts and is often added to lists like Cool Girl Names From Around the World and discussed in our forums with posts like "Three Strikes, You're Out -- Girls".
From the experts:
Popular Spanish name that relates to the patron saint of Mexico. It could conceivably, like Soledad and Consuelo, cross the border into multicultural territory, but the name's decline since the nineties would seem to make that less likely.
Guadalupe, literally "valley of the wolves in Spanish," relates to Our Lady of Guadalupe, revered in Latino culture as a protector of the Mexican people.