Sienna has been a Top 100 choice in England & Wales since 2005, the year after Sienna Miller's acting breakthrough in the hit movies Alfie and Layer Cake. In the US, it also got a big boost in the early noughties, before dropping slightly then rebounding to reach an all-time high in 2022.

Seraphina is one of the most-searched name on Nameberry, destined for even greater popularity. The highest-ranking angels, the six-winged seraphim, inspired the lovely name Seraphina.

Sadie started as a nickname for Sarah, but their images couldn't be more disparate. Where Sarah is serious and sweet, Sadie is full of sass and fun.

Although Sylvia seems to be having somewhat of a revival among trendsetting baby namers, we'd still opt for the even gentler and more unusual Sylvie. Despite being dated in its native France (where it was popular during the 1950s and 60s), in English-speaking regions it still feels fresh and international without being unfamiliar and has a cosmopolitan, international air. It debuted on the US Top 1000 in 2016.

Sophie is the French form of the Greek Sophia, for which it is also commonly used as a nickname. Given Sophia's long standing among the Top 10 girl names in the US, Sophie may feel more popular than it actually is.

Stella is a name with star quality and sparkle, that manages to sound both ethereal and earthy. Celestial but not otherworldly, it lands somewhere between the popular Ella and bold Seraphina.

Sophia, which was the Number 1 girls' name in the US from 2011 to 2013, is among the top girl names in the Western World, with a sensuous sound and high-minded meaning. A real winner, Sophia reached the top of the charts without losing any—okay, much—of its sophisticated beauty.

Sofia is a refined variation of the Greek name Sophia, which was derived directly from sophia, the Greek word for wisdom. It was the name of a Roman saint—the mother of Faith, Hope, and Charity—and queens of Russia and Spain.

Sage is an evocatively fragrant herbal name that also connotes wisdom, giving it a double advantage. It entered the Top 1000 at about the same time for both genders in the early 1990s, but it has pulled ahead for the girls. Toni Collette named her daughter Sage Florence.

Scarlett Johansson is doing more for this sparky southern name than Scarlett O'Hara ever did. Since the turn of the 21st century, Scarlett has gone from an obscure literary name to one of the most popular girls' names starting with S, right after longtime favorites Sophia and Sofia.

The musical, sylvan Sylvia seems poised to join former friends Frances and Beatrice and Dorothy back in the nursery.

With its sassy, old school vibes, its cheerful, snappy sounds, and its fresh, unisex image, Scottie was one of the fastest rising names for girls in the US in 2023, and then again in 2024.

A concise choice with a hint of chic, Sabine is the French, Dutch, and German form of the Latin Sabina. While it has never charted in the US, Sabine saw a slight increase in use in recent data, with 107 babies given the name (compared to 70 called Sabina).

The image of the lovely Lady Sybil, tragic youngest daughter of the Crawley family on Downton Abbey is likely to go a long way towards reviving this almost forgotten name, off the list since 1966 and most popular in the 1920s and '30s.

Simone, the elegant French feminization of Simon, strikes that all-important balance between unusual and familiar, and it's oozing with Gallic sophistication. A dated choice in its native France, gymnast Simone Biles brings new bounce and spark to name.

Although Susan had her heyday from the thirties to the sixties, and is now common among moms and new grandmas, and though most modern parents would prefer Susanna/Susannah, we have spotted some flickers of interest in a revival. It still retains a certain black-eyed-Susan freshness.

This is a soft, soignée French girls' namethat has become familiar here via singer Solange Knowles, younger sister of Beyonce.

Sarah was derived from the Hebrew word sarah, meaning "princess." Sarah is an Old Testament name — she was the wife of Abraham and mother of Isaac. According to the Book of Genesis, Sarah was originally called Sarai, but had her name changed by God to the more auspicious Sarah when she was 90 years old.

Serena, a name used since Roman times, was given fresh life by tennis star Williams, and then again with the leading character on Gossip Girl, Serena van der Woodsen. There have also been Serenas on soap operas and other shows from Bewitched to Law & Order.

As a Japanese name, Suki has the sweet meaning "loved one". It's also an English diminutive of Susanna, making it a creative and modern way to honor a Susan in your life.