Xerxes Break, character in anime "Pandora Hearts"
Xerxes, pet eel of Mozenrath in Disney's Aladdin TV series.
Xerxes, boy representing X, who got eaten by mice, in The Gashlycrumb Tinies by Edward Gorey
Xerxes, pet falcon of PeterGriffin in an episode of TV's "Family Guy"
Xerxes, ancient civilization in Fullmetal Alchemist: Brotherhood where the entire population was mysteriously wiped out in one night
"Xerces," Song by the Deftones
"Xerxes," Composition by composer JohnMackey.