The name Lois is a girl's name of Greek origin meaning "most desirable". Lois and is often added to lists like Bible Names for Girls and discussed in our forums with posts like "Drop you least favourite (girls with middles)".
From the experts:
The eternal fiancee of Superman turned sweet gray-haired lady who's always available to babysit her grandkids. Lois is actually a New Testament name of Greek origin: she was converted by Paul and was the grandmother of Timothy, who became one of Paul's disciples. Other s-ending names are making a comeback, as is Louise, so why not Lois?
Lois was a Top 20 name in the 1920s and stayed in the Top 50 into the 1940's, but dropped off the list completely in 1983.