A place name with a deep Southern accent, the once-obscure Savannah shot to fame, with others of its genre, on the heels of the best seller Midnight in the Garden of Good and Evil, which was set in the mossy Georgia city of Savannah. Originally a substitute for the overused Samantha, Savannah is now popular itself, long among the top girls' names starting with S.

Sierra is a name borrowed from the western mountain range, with Latin rhythm and cowboy charm, that has led to many offshoots: Cierra, Cyara, and so on. It is now probably past its peak but retains its pretty-yet-strong sound. The meaning refers to the sharp, irregular peaks of some of the Western mountains such as the Sierra Nevada.

A bright and warm possibility for a summertime girl, Solana feels both soulful and fresh, distinctive and familiar. Originally adapted from the Spanish surname and Saint name, Solano, it entered the US Top 1000 for the first time in 2023.

Santi is a cute short form of these names popular in Central and South America, but it can also be considered a Thai name, meaning "peace".

Santiago is a spirited Spanish name with great crossover potential. It's a place-name (a city in Chile), a surname, and the name of the patron saint of Spain.

Widely heard in both Italian and Spanish households, Sergio and his many international brothers are rooted in Sergius, one of the original Roman family names. The meaning is unknown, but possibly is related to servant or protector.

This original form of the name -- the more familiar Sylvia spelling came later -- seems more modern now.

The Spanish and Portuguese variation of the all-saints name. Santos is a name that has appeared in the US Top 1000 every year except for two: 1913 and 1915.

Serafina is a name so lovely it's worthy of an angel. But the more stylish spelling today is Seraphina.

A common epithet of Christ, frequently heard in the Hispanic community, Salvador could also be a great choice for artistic parents, given the continuing popularity of Dada and Surrealist painter Salvador Dalí. (If Monet and Raphael get a look in, why not Salvador?)

Savanna has lost ground in recent years. It remains eclipsed by its more traditionally spelled cousin Savannah.

This strong Spanish name that refers to the Virgin Mary (Our Lady of Solitude) has been made accessible by broadcaster Soledad O'Brien -- who shows how well it combines with an Anglo surname. Her birth name was Maria de la Soledad Teresa O'Brien.

This name of a famous ancient Roman jurist is sometimes heard in the Hispanic community.

Sierra is a name borrowed from the western mountain range, with Latin rhythm and cowboy charm. It is now probably past its peak for girls, but remains a striking nature-inspired choice for boys, with a strong, surprising and energetic sound. The meaning refers to the sharp, irregular peaks of some of the Western mountains such as the Sierra Nevada.

Serafin and Seraphim are much less known and used in the US than the feminine forms Serafina and Seraphina, but just as appealing. An out-of-the-box Spanish option with a deep history and an animated meaning.

Sefarina is dramatic and feminine, but Serafina is far more commonly used. Think of Sefarina as deriving from Zephyr, which can be used as a male name; the female version is Zephyrine or Zephyrina, or the Portuguese Zeferina.

Variant of Sylvana

A shiny and sylvan choice, this sleek yet spirited name feels familiar yet is rarely used.

The forerunner of Cynthia is all but unknown these days, but deserving of import and revival.