Place name, American variation of Holstein, German
"dwellers in the wood"

Holston Origin and Meaning

The name Holston is a boy's name meaning "dwellers in the wood".

Holston is a uniquely Southern place name — that of a river, lake, and mountain in Tennessee, as well as a town in Virginia. Holston was first used for the river, previously called the Cherokee River. It was adapted from the surname of pioneer Stephen Holstein, who resided alongside the river. Holstein was the name of a Saxon tribe and is now a region in Germany.