Lady, cocker spaniel in Disney's "Lady & the Tramp"
Lady Deathstrike, character in Marvel's X-Men comics
LadyLark, character in the Marvel's Squadron Supreme comics
Lady Octopus aka Carolyn Trainer, character in Marvel Comics
Lady, character in video game Devil May Cry 3: Dante's Awakening
Lady, direwolf belonging to Sansa in the "Game of Thrones" series
Lady, Victorian-style steam engine in animated series Thomas the Tank Engine
Lady Antebellum, American country music band