Alaska is a state name that's gaining a following, along with Montana and Dakota. While it was used exclusively for girls in the 2020 US name statistics, there's no reason it can't work just as well for boys.

Alaska

Azul is the Spanish word for "blue" and was first recorded as a baby name (for girls) in 1995. It's technically considered unisex today, although it is still much more common as a feminine name.

Azul

Antalya

Atlanta

Edgy German capital with definite possibilities as a baby name. 

Berlin

Cairo is an exciting place name possibility with upbeat o ending. It debuted in the US Top 1000 in 2015 and keeps heading upward.

Cairo owes its sudden popularity to its choice by rapper Tyga for his son King Cairo's middle name. And Brazilian place kicker Cairo Santos helped popularize the name when he joined the Chicago Bears football team. Santos is named for his father, also Cairo.

Another influence propelling Cairo up the ladder: the popularity of the name Kai. And Cai could certainly be a nickname for Cairo.

Cairo

This Mediterranean island name would be a plausible choice for parents with a Greek or Turkish heritage. 

Cyprus

With Galway and Ireland in play as names (not to mention Shannon and Kerry), there's no reason this one can't work, too. 

Dublin

Florence is historically a unisex name, deriving both from Latin Florentius and Florentia. Although much more commonly feminine in modern times, it appeared in the US Top 1000 for boys until 1914. 

 It's also a geographical name, belonging to the famous Italian city. J. K. Rowling used the Italian version, Firenze, for a centaur in the Harry Potter series.

Florence

The name of the great Renaissance astronomer and mathematician would make a distinctive hero-middle-name for the son of parents involved in those fields. 

Galileo

An undiscovered place-name with an appealing o-sound ending. 

Glasgow

Geneva

Guadalupe 

Looking for a Texas name more distinctive than Austin and Dallas?  Houston is a lanky, roguish place-name, right in style with its Texas accent and cowboy image.

Houston

Transferred use of the geographical name Jerusalem, which is a sacred city in many religious traditions, including Judaism, Christianity and Islam. It is given to around a dozen babies of each sex per year in the US.

Jerusalem

Junín

Japanese city name not yet on the map for babies, but why not?

Kyoto

In the US, London is popular for both sexes, though as the name rises for girls, it's levelled off for boys. Of course, London is far less popular in  the UK and other English-speaking countries.

London

Lima

The Islamic prophet Muhammad was born in the city of Mecca, now known as the holiest city in Islam. Millions of Muslims make a pilgrimage to Mecca each year, which is in modern-day Saudi Arabia. Non-Muslims are not allowed inside the city.
 
The etymology of Mecca is uncertain, but it most likely derived from an Old South Arabian root meaning "temple."
 
Mecca first appeared on the baby name charts in 1952 but was most popular in the 1990s, particularly among baby girls. Today it is used roughly equally between the sexes.

Mecca

Melbourne

A place name with so much history, from Ancient Egypt, where so many pyramids were built, to the US blues southern city. The name also has a great meaning. Although it's being given to babies of both genders, Memphis (unlike most place names) is much more common for boys than girls.

Memphis

Mendoza has great potential to move from a surname to a first name for either sex. It is derived from the Basque words mendi, meaning "mountain," and hotz, "cold."

Mendoza

As Mila rises for girls, so Milan is becoming a more popular option for boys, especially after singer Shakira chose it for her son. After a 55-year hiatus, it reentered the Top 1000 in 2013 and is heading dramatically upward.
 
Milan has been a Top 10 name for boys in The Netherlands and Hungary, as well as making the Top 20 in Belgium. A famous literary namesake is Czech writer Milan Kundera, author of The Unbearable Lightness of Being. In America, it is a solidly unisex name whose usage is no doubt also inspired by the stylish Italian city of the same name.

Milan

Madrid

Mercedes

Munich

Nazareth, an important place in the New Testament as the hometown of Jesus, is on the rise as a name for both girls and boys. It's one of a handful of Biblical place names, along with Galilee and Jericho, stylish among contemporary Christians.

Nazareth

With so many other places translating to first names, why not this major Japanese city -- especially if it holds some personal significance. 

Osaka

Olavarría

Orlando

Portland

Prague

A Greek island and a prestigious scholarship make an upper-crusty first name with the uber-stylish S ending. Rhodes was recently chosen by actress Emma Roberts for her son, born in 2020, but it has also started to be given to a small number of girls each year too.

Rhodes

Rio is one of Japan's most popular girls names, constantly sitting in that country's Top 10. Of course, Rio may also stem from the Portuguese and Spanish word for river, and the Brazilian city Rio de Janeiro. A truly international name for a cosmopolitan baby!

Sydney was a hot girls' name in the 1990s, but she's arguably still cool. One of the original old man names adopted for baby girls, Sydney's popularity may be down but she's not out. 
 Cool girl actress Sydney Sweeney, of Euphoria and White Lotus, is doing a lot to burnish Sydney's image. The city of Sydney, Australia is another familiar reference.
 Katharine Hepburn played a female Sidney in her first movie, A Bill of Divorcement and lately there have been women named Sydney all over the big and small screens, including Annette Bening in The American President, and on Alias, Parenthood and Hope and Faith.
Actor Sidney Poitier named his daughter Sydney back in 1973,

Sydney

Taipei

Tuscany

This name of one of the most romantic cities in the world could easily find its way onto an American baby girl's birth certificate. 

Venice

Vienna is one of the more popular of the European place-names, with a particularly pleasant sound, evoking elegant images of the Blue Danube, of castles and cafes, sweets and sausages and Strauss waltzes—and Sigmund Freud. It could be a possible substitute for the popular Sienna. 
 While many see place-names as a recent invention, Vienna has been used as a name for centuries. It was, for instance, the name of a 15th century mother of a saint. Joan Crawford plays a strong-willed saloon keeper in the classic 1954 western drama Johnny Guitar. And there was also a Vienna in the F. Scott Fitzgerald story "The Bowl."
 Trivia tidbit: Vienna's Roman-era name was Vindobono.

Vienna

Xiamen

Zhuhai

Arcane 's list "Unique Location Baby Names" of 42 great name ideas: Alaska - Zhuhai!

Unique Location Baby Names

Town/City/Country names (and variations) I feel could fit as first and/or middle names! I'm not familiar with cultural significance these names might hold so I apologize for any mistakes, I just made a list I thought sounded cool 