Though most Mels are playing pinochle with Murray and Morris, there was a notable Saint Mel. He is one of the earliest Irish saints, a nephew of St. Patrick. He became a priest, then built a great monastery where he served as abbot.

Not one but two Spice Girls are named Mel, which led to it briefly being more popular for girls than boys in the 90s and early 00s, but it has now fallen out of favor for both sexes.