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Gender: M Origin of Spence: Short form of Spencer

Spence is occasionally used as a name all on its own and it has more of a sense of completeness than many nickname-names.

Famous People Named Spence

Michael Spence, winner of the Nobel Memorial Prize in Economics

Pop Culture References for the name Spence

Holden Spence, from the movie "Everyone Says I Love You"
Spence Olchin, from the TV series "The King of Queens"
Nickname of Spencer from iCarly