Sisto

Sisto is a masculine name of Italian and Spanish origin, derived from the Latin name Sixtus, meaning 'sixth.' The name has historical significance in Catholic tradition, as six popes have taken the name Sixtus (or Sisto in Italian). The most famous was Pope Sixtus V, who played a crucial role in the Counter-Reformation and in the development of Baroque Rome. While relatively uncommon outside of Italy and Spanish-speaking regions, Sisto has a strong, distinctive sound with its crisp consonants. The name carries an air of classical dignity and Mediterranean charm. For families with Italian or Hispanic heritage, Sisto represents a connection to cultural roots while offering a less common alternative to popular names.

Pronounced SIS-toh.

As of October 2026, Sisto ranked #12335 in US births in 2008 SSA, peaked at #1913 in 1935.