Guadalupe is a river in Spain, the name of which is derived from the Arabic phrase Wad-al-lubb, meaning "hidden river." Alternatively, it may come from a combination of the Arabic word wadi, meaning "valley" or "river," and the Latin lupus, "wolf."

Popular Spanish name that relates to the patron saint of Mexico. It could conceivably, like Soledad and Consuelo, cross the border into multicultural territory, but the name's decline since the nineties would seem to make that less likely.