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Gender: M Meaning of Twain: "divided in two" Origin of Twain: English

Twain can be thought of as a modernization (and possible namesake) of the dated Wayne, seasoned with the humor of Mark Twain, who adopted it from a river term.

Famous People Named Twain

Mark Twain, pen name of American writer Samuel Langhorne Clemens (which he based on the cry of a Mississippi leadsman calling out the depth of the river at a particular point)
Shania Twain (birth name Eilleen Regina Edwards; Twain was the surname of her stepfather, an Ojibwa), Canadian country music singer

Pop Culture References for the name Twain

Twane, Tway, Trawyne, Tawine, Twayn, Twaine, Twan