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Spike is part mid-century nickname-name, ala Buster or Buck, and part word name, with an all-over cool creative dude feel thanks to directors Spike Lee and Spike Jonze. Mike Myers named his son Spike. That's right: Spike and Mike.

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Famous People Named Spike

Spike Lee, American director
Spike Jonze, American director
Spike Mendelson, American chef and restaurateur
Spike Bowman Smith, son of Edith Bowman & Tom Smith

Pop Culture References for the name Spike

Spike, character on "Buffy the Vampire Slayer"
Spike, a baby dragon on "My Little Pony: Friendship Is Magic"
Spike, Kendall's baby on "All My Children"
Spike Milligan, ex-burglar, friend to Jimmy Pitt, in P. G. Wodehouse's "A Gentleman of Leisure" (1910)
Spike, a word for 'sharp point'.
Spike Spiegel, main character from anime series "Cowboy Bebop"
Spike Freeman, from the Australian TV series "Snobs"
Spike, Rhynoc boss from game "Spyro the Dragon"
Spike Scarlatti, character on TV series "Flashpoint"