Wayne Gretzky, Canadian hockey player
Wayne Newton, American singer
Wayne Brady, American singer, comedian, and actor
Wayne Hardnett, Jr. aka Bone Crusher, American rapper Lil Wayne (born DwayneCarterJr.), American rapper
Wayne Richard Ferreira, South African tennis player
Wayne Rooney, English footballer
Wayne Shorter, American jazz saxophonist
Wayne Arthurs, Australian tennis player
Wayne HamiltonBlack, Zimbabwean tennis player Matthew Wayne "Matt" Shepard, American murder victim
Wayne Rigsby, character on TV's "The Mentalist" Bruce Wayne aka Batman, superhero
Wayne Campbell, main character in "Wayne's World" series
Wayne Arnold, oldest boy on TV's "The Wonder Years"
There are apparently more serial killers with the middle name Wayne than any other.