Esprit (pron. ÃÂ-SPREE), a French cognate meaning "sprightliness of spirit or wit; lively intelligence", used as a religious unisex name in France in the 19th and early 20th centuries
"Spirit: Stallion of the Cimarron," 2002 animated film about a wild horse, voiced by MattDamon Mariko "Spirit" Tanaka, character in Wing Commander video game series
"The Spirit," crimefighter in a comic by Will Eisner
Spirit, the original name of Deathscythe in manga "Soul Eater"