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Gender: F Meaning of Sissy: "sister" Origin of Sissy: Diminutive of Cecilia; pet name for "sister"

Old-fashioned nickname for a sister, almost never heard today.

Famous People Named Sissy

Mary Elizabeth "Sissy" Spacek, American actress

Pop Culture References for the name Sissy

Sexist slang for wimp
Sissy, from movie "Jay and Silent Bob Strike Back" played by Eliza Dushku
Sissy Sullivan, character from the 2011 drama film "Shame"
Sissy Rommely, character from A Tree Grows in Brooklyn

Cissie, Cissey, Sissey, Sissie, Sissee, Cissy, Cissi, Sisi, Sisie