Reuben

Reuben is a rich and resonant underused Old Testament choice with several ingredients for success: its biblical pedigree as Jacob's first born son by Leah and the founder of one of the tribes of Israel, the distinction of never having been heavily used, and a friendly, down-home image. Maybe the current crowd of Jacobs will grow up and follow their biblical namesake by calling their own sons Reuben.

Only downsides: Reuben is also known as a sandwich, and is the source of the word 'rube.'

Panama-born salsa singer Ruben Blades represents the Latin version (with the accent on the second syllable); Reuven is the name in Hebrew.