Ramona is a Sweet Spot name--neither too trendy nor too eccentric. Kids will associate it with the clever Ramona Quimby character in the series of books by Beverly Cleary, also seen on TV. It was chosen by starcouple Maggie Gyllenhaal and Peter Sarsgaard for their little girl, who would be joined by sister Gloria.
Ramona came into prominence in the 1880's via the beautiful half Native American heroine of the best-selling eponymous romance novel by Helen Hunt Jackson, played on screen by Loretta Young. and others.
Trivia tidbit: Ramona is the middle name of singer Avril Lavigne.
Ramona was in the Top 1000 through the 1980's, but it reached its peak in 1928 at Number 117.