Nessarose, or "Nessa," sister of Elphaba the Wicked Witch of the West in the musical "Wicked"
Nessa, character from "Gavin & Stacey"
Nessa, one of the Valar ("angels") from Tolkien's Legendarium
NessaStein, main character of the British miniseries "The Honourable Woman"
NessaHolt, character from TV series Las Vegas