Nathaniel "Nate" FitzwilliamArchibald, a main character in the Gossip Girl book and television series Nathaniel "Nate" Grey, character in X-Men comics
Nate Getz, character on television show NCIS: Los Angeles
Nate Fisher, character on television series Six Feet Under Nathan "Nate" Ford, main character on TNT's Leverage
Nate Wright, main character in book series and comic strip "Big Nate"
Nate the Great, book series about a kid detective by Marjorie Weinman Sharmat
Nate River aka Near, character in the anime/manga "Death Note"