Margo, played by Miranda Cosgrove in the movie 'Despicable Me'
Margo Roth Spiegelman, the female lead of JohnGreen's novel Paper Towns.
Margo, character in "Lars and the Real Girl"
Margo Dowling, film star in the "U.S.A." trilogy (1930-36) by John Dos Passos
Margo Pike, MalloryPike's sister in the Baby-Sitters club series by Ann M. Martin
Margo Masse, from movie "Fear" played by AlyssaMilano