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Gender: M Meaning of Keefe: "handsome and noble" Origin of Keefe: Irish

Popularity: this week.

Keefe is an energetic Irish surname occasionally used as a first. Only caveat: Will people think your little Keefe is a Keith with enunciation problems?

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Famous People Named Keefe

Pop Culture References for the Name Keefe

Keefe was a frightening antagonist on one episode of late '90s Nickelodeon cartoon "Invader Zim"

Keeffe