Gwen Stefani, American singer and fashion designer
Gwen Guthrie, American singer
Gwen John, Welsh artist Gwendolyn "Gwen" Ifill, American journalist Gwenyth "Gwen" Verdon, American actress of the 50s-60s
Gwen Stacy, love interest of Spider-Man
Gwen Cooper, Torchwood character
Gwen Dawson, Downtown Abbey character
Gwen Tennyson, from Ben 10
Gwen Grayson, from 2005 movie Sky High
Gwen Raiden, from the TV series Angel
Gwen Norbeck, from As the World Turns
Gwen Van Osburgh, character in The House of Mirth (1905)
Gwen Thompson, best friend of 2009 American Girl of the Year ChrissaMaxwell
Gwen, character from movie "Ghost Town"
Gwen Cummings, from movie "28 Days"