Fran Fine, character on TV's "The Nanny" played by Fran Drescher
Frances "Fran" Sinclair, mother on sitcom "Dinosaurs"
Fran Katzenjammer, character from British TV series Black Books
Fran Stalinovskovichdavidovitchsky, character in the movie "Dodgeball"
Fran Carvey, character in the movie "The Getaway"
"Kukla, Fran and Ollie," TV puppet show starring FranAllison "Fran," 1985 Australian movie
Fran, character from the video game Final Fantasy XII
Fran, red squirrel from Disney's "Higglytown Heroes"
FRAN (Friendly Replicator Android), character in TV's "Stargate Atlantis"
Fran, character in video game "Inazuma Eleven GO VS Danball Senki W."
FranBow, from the eponymous video game