Brenda Lee, American pop singer
Brenda Blethyn, English actress
Brenda Song, American actress
Brenda Strong, American actress
Brenda Lea Turnbaugh, American actress; twin sister Wendi Turnbaugh
Brenda Jean Bakke, American actress
"Brenda's Got a Baby," song by Tupac
Brenda LeighJohnson, main character on the detective show "The Closer"
Brenda, Tony Last's unfaithful wife in "A Handful of Dust" (1934) by Evelyn Waugh
Brenda Montgomery, a character in the Quebecer parody show "Le coeur a ses raisons".
Brenda Walsh from "Beverly Hills 90210"
Brenda Jenkins, character from TV series 227