"Brenda's Got a Baby," song by Tupac
Brenda LeighJohnson, main character on the detective show "The Closer"
Brenda, Tony Last's unfaithful wife in "A Handful of Dust" (1934) by Evelyn Waugh
Brenda Montgomery, a character in the Quebecer parody show "Le coeur a ses raisons".
Brenda Walsh from "Beverly Hills 90210"