Kyrie elieson is one of the oldest religious refrains, meaning Lord, have mercy. As a first name, though, Kyrie is less a name of God and more a nickname-name that might be short for Kyra or a diminutive that stands on its own, a la Kylie. The best-known Kyrie is the male basketball player Kyrie Irving, who pronounces the first syllable to rhyme with my rather than fear. He has inspired more than 1000 baby boys to be given this name one recent year in the US, while it was given to 178 baby girls. Impressive numbers.